What's included in your toxicological risk assessment
Ingredient-level toxicology and Margin of Safety for one beauty product, built to feed your CPSR.
Signed toxicological summary report
Every ingredient analysed and the report signed by a qualified Safety Assessor
Margin of Safety table
NOAEL, Systemic Exposure Dose (SED) and MoS set out for each relevant ingredient
Exposure assessment
Exposure modelled for your product category, application area, frequency and leave-on or rinse-off use
Formulation safety conclusion
A consolidated judgement on whether the formula is toxicologically safe for its intended use
CPSR-ready format
Laid out to match the exposure and toxicology sections of CPSR Part A
Choose your service
Fixed prices online. Choose your delivery speed on the next page.
All-in-One Cosmetic Product Safety Report CPSR, PIF, SDS & UK/EU Notification
Cosmetic Product Safety Reports (CPSR) for Beauty Products
Cosmetic Product Safety Reports (CPSR) for Beauty Products with Variations
CPSR Cosmetic Product Safety Reports for Fragrances and Perfumes
Toxicological Risk Assessment (TRA) for Beauty Products
Cosmetic Product Formulation Review
Children Product Certificate (CPC)
Allergen Compliance Check for Cosmetic Products
How it works
Fill our Product Information Document
Give us your product details and upload your formula and raw-material data.
Ingredient data review
We profile each ingredient using SCCS opinions, ECHA dossiers, supplier data and Annexes II–VI.
Exposure and Margin of Safety
We model exposure for your product type and calculate SED and MoS for each relevant ingredient.
Signed report delivered
You receive the signed TRA within the 72, 48 or 24 hours of the delivery option you chose.
Not sure which documents you need?
Tell us about your product and markets and we will tell you exactly what is required.
Frequently asked questions
Straight answers to what brands ask us most.
Send us your product details and a safety assessor will reply.
What is a toxicological risk assessment for cosmetics?
It is a scientific evaluation of each ingredient's hazards and the consumer's exposure to it, expressed as NOAEL, Systemic Exposure Dose (SED) and Margin of Safety. It forms the toxicology section of a cosmetic product safety report (CPSR).
Is a TRA the same as a CPSR?
No. A TRA covers ingredient exposure and toxicology. A CPSR is the full Annex I safety report, which also covers stability, microbiological quality and packaging, and ends with the safety assessor's signed Part B conclusion.
Do I need a TRA for my CPSR?
Not as a separate order. Every CPSR must contain a toxicological evaluation, and our CPSR includes it. Order a standalone TRA when you need the toxicology before your formula is final or to settle a question about one ingredient.
Can I sell a cosmetic with only a TRA?
No. Article 10 requires a safety assessment and a complete CPSR before a cosmetic is placed on the UK or EU market. A TRA supplies part of that evidence but does not replace the report.
How is the Margin of Safety calculated for a cosmetic ingredient?
The Margin of Safety is the NOAEL divided by the Systemic Exposure Dose. Under the SCCS Notes of Guidance, an MoS of at least 100 is generally regarded as acceptable for systemic effects.
How much does a cosmetic TRA cost and how long does it take?
It costs £75 with delivery within 72 hours. Delivery within 48 hours costs £100, and within 24 hours £150.
What do you need from me for a TRA?
Your full INCI list with percentages, the SDS for every raw material, the product category, whether it is leave-on or rinse-off, and where and how often it is applied.
Which guidance does a cosmetic TRA follow?
The SCCS Notes of Guidance for the Testing of Cosmetic Ingredients and their Safety Evaluation (12th Revision), using data from SCCS opinions, ECHA dossiers and studies run to OECD test guidelines.